Breast Pathology, Molecular Pathology And Autopsy Pathology
Pathology and Forensic Medicine
At the Pathology And Forensic Medicine department office
Appointment on Visitation important
Topic: Breast Pathology, Immunohistochemistry/ Molecular Pathology And Autopsy Pathology
Description: Some research articles authored or co-authored by me have been published in breast pathology, immunohistochemistry/molecular pathology and autopsy pathology subspecialties of Pathology. There are on-going researches in these areas, which also include collaborative work with Universities within and outside the Country. Currently, a clinical trial on breast cancer, assessing the response rate of neoadjuvant taxotere and trastuzumab in Nigerian women with her-2 positive breast cancer ARETTA in collaboration with the University of Chicago is a project in which i participate as a Pathologist.
|NATIONAL POSTGRADUATE MEDICAL COLLEGE OF NIGERIA
HORMONE RECEPTORS AND HER-2/NEU OVEREXPRESSION IN BREAST CARCINOMAS IN PATIENTS OF WEST AFRICAN ORIGIN SEEN AT LAGOS STATE UNIVERSITY TEACHING HOSPITAL, NIGERIA
SANNI D Ayodele, Popoola O Abiodun, IBRAHIM A Nasiru, OMODELE O Foluso, EMIOGUN E Festus, OLUDARA A Mobolaji, OBAFUNWA J Oladapo. Breast carcinoma is a disease of utmost concern to the family and society at large. The current trend in the management of breast carcinoma involves hormonal therapy. Consequently, the hormone expression of the tumour in the individual involved must be known if she or he is to benefit from such therapy. This is a prospective study of oestrogens and progesterone receptors as well as Her-2/neu overexpression of all breast carcinomas seen at Lagos State University Teaching Hospital, Ikeja between 1st April, 2016 and 30th September, 2018. One hundred and seven cases were analysed, comprising of 105 females and 2 males with an age range of 26 to 88 years. They expressed ER, PR and HER-2/NEU positivity in 42.1%, 33.6% and 30.8% respectively. This study shows that breast carcinomas occured predominantly in females of younger age and present with tumours, most of which were of high grade and exhibit triple negativity. This observation is important in therapeutic decisions and management of patients. Early detection of the disease through breast cancer screening programmes should be improved upon. Manuscript submitted to Diagnostic Pathology Journal. Abstract accepted and presented at College of American Pathologists CAP19 conference at Orlando, Florida on September 21-25, 2019 and published as a web-only supplement to the September 2019 issue of the Archives of Pathology Laboratory Medicine.
SANNI DANIEL is a Senior Lecturer at the Department of Pathology and Forensic Medicine
SANNI has a FMCPath in PATHOLOGY from NATIONAL POSTGRADUATE MEDICAL COLLEGE OF NIGERIA