OSUNDIYA MEDINAT OLUBUNMI

Chemistry

At the Chemistry department office

Appointment on Visitation important

Topic: MICELLAR CHARACTERIZATION, EQUILIBRIUM BINDING CONSTANT, AND THERMODYNAMICS STUDIES OF SOME AMPHIPHILIC AND HYDROPHOBIC DRUGS

Description: The solubilization of organic compound in surfactant micelles is quite important in industrial applications being valuable in pharmaceutical formulations as a tool to improve the solubility of amphiphilic and hydrophobic drugs, and to protect them from degradation has been a subject of concern. Inorganic salts are present as different sodium salts in variable quantities in the intra and extra cellular biological fluid, hence the therapeutic effect of some drugs is often optimized by derivatization through conversion into a salt form using inorganic salts Aim: To determine how ionic surfactants can influence biological events. Study of the interaction of a broad spectrum antibiotics tetracycline hydrochloride and amitriptyline hydrochloride with hexadecyltrimethylammonium chloride in aqueous and solution of salts KCl over a temperature range of 298.1 K to 313.1 K. Methodology: Conductance measurement. i Characterization of the simplified model of bio membranes drug-micelles system through a the determination the critical micelle concentration b determination of the aggregation number c evaluation of interaction parameters, d evaluation of drug-micelle composition and e the thermodynamics stability of the drug-mediated micelles. The micelle-encapsulated drug is expected have improved solubility, thereby making it bioavailable at low dosage

#	Certificate	School	Year
1.	Ph.D (Physical Chemistry)	Adekunle Ajasin University, Akungba-Akoko, Ondo State	2016

EVALUATION OF THE CORROSION EFFICIENCY OF QUARTENARY BASED IONIC SURFACTANT FOR LOW CARBON STEEL IN ACID PICKLING ENVIRONMENT

INTRODUCTION: Corrosion is an interaction between a material and its environment that results in a degradation of the physical, mechanical or even esthetic properties of the material The loss of metal integrity due to corrosion is a serious industrial challenge, Corrosion inhibition technology is one of the reliable and cost effective corrosion mitigation strategies., hence metal corrosion inhibition is primaryily important for economic maximization and environmental preservation.AIM: Mimicking acid cleaning storage using CTABEXPERIMENT: N-80 carbon steel ms sample was purchased from Erdmir Steel Co Turkey, the sample was cut into coupons of 3 cm x3 cm, the surfaces of the steel were abraded, and mechanically polished using emery papers 60, 180, 340, 600, 800, and 1200The polished steel were rinse with distilled water and acetone, and the were kept inside desiccator before use .5 mM CTAB was prepared in using acetonitrile Six 6 150 ml bottles were fill with100 ml I M HC, different concentration using serial dilution of the inhibitor, CTAB were added to each of the bottles contain two 3 cm x 3 cm coupon specimen. The experiment was observed as a function of time and temperature.RESULT: Mean wait lost, the highest percentage efficiency,.the coverage area were obtained at 24 hours and at , 1.0x 10-6 M, CTAB.CONTRIBUTION TO KNOWLEDGE: cationic surfactant of linear origin can be used as corrosion inhibitor of mild

OSUNDIYA MEDINAT is a Senior Lecturer at the Department of Chemistry

OSUNDIYA has a Ph.D in Physical Chemistry from Adekunle Ajasin University, Akungba-Akoko, Ondo State