OMISANJO OLUFUNMILADE AKINFOLARIN

Surgery

At the Surgery department office

Appointment on Visitation important

Topic: Pathological Correlation Between The Prostate Biopsy And Post Radical Prostatectomy Specimens Of Nigerian Men With Prostate Cancer

Description:

This study aims to evaluate the pathological correlation between the prostate biopsy and post radical prostatectomy specimens of Nigerian men with prostate cancer. This is in order to investigate if there is any upgrading of the cancer between the time of diagnosis and the time of surgical treatment of the cancer.

#	Certificate	School	Year
1.	FWACS ( Fellowship of the West African College of Surgeons ) (Surgery ( Urology ))	University College Hospital, Ibadan Nigeria/West African College of Surgeons	2006

Complications Following Prostate Biopsy - A Five Year Review

 This was a study to investigate the complication rates following prostate biopsy at the Lagos State University Teaching Hospital Ikeja over a 5 year period. The study will also look into the risk factors that are statistically significant for the occurrence of complications following prostate biopsy

Results

The clinical records of a total of 258 patients were available for review.

The mean age was 68.2years (range 45 to 81years). The mean and median PSA were 560ng/ml and 57ng/ml respectively (range 2.05 to 15,400ng/ml).

The prostate biopsy was transrectal in all cases. All the patients had empirical intravenous prophylactic antibiotics. All the patients had a caudal block. One hundred and seventeen (45.3%) had a comorbidity. The commonest comorbidities were hypertension (73.5%) and diabetes (18.8%).

The mean prostate size was 109gms. Most of the prostate biopsy were done by resident doctors (95%, n=145). The size of trucut needle used was size 16 in 121 patients (46.9%) and size 18 in 125 patients (48.4%). The mean number of biopsy cores taken was 10 (range 4 to 15).

The histological diagnosis was Carcinoma of the Prostate in 136 patients (52.7%) and Benign Prostatic Hyperplasia in 100 patients (38.8%). Twenty four patients (9.3%) had complications. The complications were sepsis (3.1%), rectal bleeding (2.3%), haematuria (2.3%) and acute urinary retention (1.6%). Thirteen patients needed hospitalization (5%). There was no mortality.

The incidence of sepsis was statistically significantly higher with increasing the number of cores taken (p=0.000), but there was no significant difference in the incidence of sepsis with the size of the trucut needle used (p= 0.299).  The incidence of rectal bleed correlated negatively with the patients’ age (p=0.014).

OMISANJO OLUFUNMILADE is a Associate Professor / Reader at the Department of Surgery

OMISANJO has a FWACS ( Fellowship of the West African College of Surgeons ) in Surgery ( Urology ) from University College Hospital, Ibadan Nigeria/West African College of Surgeons