Meet OJEWALE ABDULFATAI OLAKUNLE, an Academic Staff of Lagos State University.


Endocrine And Reproductive Anatomy


Lecturer II




At the Anatomy department office

Visiting Hour

Appointment on Visitation important

Research Interest

Topic: Endocrinology And Reproductive Biology

Description: Contributions to the areas of endocrinology, reproductive biology, physical anthropology, nutraceutical, and alternative medicine.


# Certificate SchoolYear
1. Ph.D (Endocrine and Reproductive Anatomy) Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria 2019

Current Research

Mitigating roles of Ethanolic Roots Extract of Ageratum conyzoides on Blood Glucose, Lipid Profile, Insulinotropic activities, and on Pancreatic Beta changes Cells in Alloxan-Induced Diabetic Rats

Research Details

Aim: The study investigated the modulating roles of ethanolic roots extract of Ageratum conyzoides for its antihyperglycemic, antihyperlipidemic, insulinotropic activities and on pancreatic beta cells changes in alloxan-induced diabetic rats. Methodology: Twenty Wistar rats were randomly divided into four 4 experimental groups: control, diabetic, and A. conyzoides 250 and 500 mg/kg bwt treated diabetic groups The animals in three out of four groups were fasted for 18 h and were made diabetic by injecting with a single dose of alloxan ALX 150 mg/kg, Diabetic rats 5 per group received graded doses 250 and 500 mg/kg bwt of the extracts for 28 days. Blood was collected every week for four weeks for glucose estimation. Lipid profile was measured using DiaSys Kits from Germany which utilized the colorimetric method. Insulin Assay was measured using Monobind Insulin Microplate Elisa test.Diabetic rats without treatment showed significant increases p&0.05 in the levels of blood glucose, triglycerides, total cholesterol, low density lipoprotein LDL-cholesterol while the high density lipoprotein HDL-cholesterol level were significantly decreased p&0.05 compared to normal rats. In addition, the diabetic rats treated with the Ageratum conyzoides showed significant decrease p&0.05 in blood glucose, TG and LDL cholesterol levels and a significant decrease p&0.05 in HDL cholesterol level compared to diabetic untreated rats. There were significant reductions p&0.05 in low-density lipoprotein LDL -cholesterol levels and significant increase p&0.05 in the treated diabetic group compared to the negative control. In addition, cytoarchitectural changes also revealed the protective nature of the ethanolic roots extract of Ageratum conyzoides against alloxan induced necrotic damage of pancreatic tissues.The ethanolic roots extract of Ageratum conyzoides mitigated hyperglycemic by stimulating insulin release from the beta cells of the pancreas and attenuated dyslipidemia.It contributes to the areas of experimental and clinical endocrinology, nutraceutical and alternative medicine.


OJEWALE ABDULFATAI is a Lecturer II at the Department of Anatomy

OJEWALE has a Ph.D in Endocrine and Reproductive Anatomy from Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria

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