Meet OGUNTONA SHOLA TAIWO, an Academic Staff of Lagos State University.
Medicinal Plants, Diabetic Nephrooathy, Plasmin
Lecturer I
Medical Biochemistry
At the Medical Biochemistry department office
Appointment on Visitation important
Topic: Deep Vein Thrombosis DVT
Description: Background: Deep Vein Thrombosis DVT is a significant health concern for pregnant women, as pregnancy-related physiological changes elevate the risk of thrombotic events. Dimethylmethylene Blue DMMB is being explored as a diagnostic tool to enhance early detection of DVT, which is crucial for improving maternal health outcomes, particularly in resource-limited rural settings like those found in Nigeria. Methods: A cross-sectional study was conducted involving 254 pregnant women attending antenatal clinics in Wasimi, Ogun State, Nigeria. Pregnant women in their second and third trimesters were recruited. DMMB testing was performed to identify potential DVT cases, with results confirmed using compressed ultrasonography, the gold standard for DVT diagnosis. Data analysis focused on true positive, false positive, true negative, and false negative results across both trimesters. Results: DMMB testing identified 7 true positive DVT cases, all confirmed by compressed ultrasonography scans, yielding a sensitivity of 100%. There were 3 false positive cases 1 in the second trimester and 2 in the third trimester , none of which were confirmed by compressed ultrasonography scans. The specificity of DMMB was 99.0% in the second trimester and 98.6% in the third trimester, with an overall specificity of 98.8%. The positive predictive value PPV was 75% in the second trimester and 66.7% in the third trimester, while the negative predictive value NPV was 100% in both trimesters. The overall accuracy of DMMB was 98.8%. Conclusion: DMMB shows high sensitivity and specificity in predicting DVT among pregnant women, with all true positive cases confirmed by compressed ultrasonography scans. The presence of false positives, particularly in the third trimester, underscores the need for confirmatory testing to ensure accurate diagnosis. DMMB can be an effective initial screening tool for DVT in resource-limited settings
| # | Certificate | School | Year |
|---|---|---|---|
| 1. | Ph.D () | The University of Sheffield | 2018 |
Background: Deep Vein Thrombosis DVT
Background: Deep Vein Thrombosis DVT is a significant health concern for pregnant women, as pregnancy-related physiological changes elevate the risk of thrombotic events. Dimethylmethylene Blue DMMB is being explored as a diagnostic tool to enhance early detection of DVT, which is crucial for improving maternal health outcomes, particularly in resource-limited rural settings like those found in Nigeria. Methods: A cross-sectional study was conducted involving 254 pregnant women attending antenatal clinics in Wasimi, Ogun State, Nigeria. Pregnant women in their second and third trimesters were recruited. DMMB testing was performed to identify potential DVT cases, with results confirmed using compressed ultrasonography, the gold standard for DVT diagnosis. Data analysis focused on true positive, false positive, true negative, and false negative results across both trimesters. Results: DMMB testing identified 7 true positive DVT cases, all confirmed by compressed ultrasonography scans, yielding a sensitivity of 100%. There were 3 false positive cases 1 in the second trimester and 2 in the third trimester , none of which were confirmed by compressed ultrasonography scans. The specificity of DMMB was 99.0% in the second trimester and 98.6% in the third trimester, with an overall specificity of 98.8%. The positive predictive value PPV was 75% in the second trimester and 66.7% in the third trimester, while the negative predictive value NPV was 100% in both trimesters. The overall accuracy of DMMB was 98.8%. Conclusion: DMMB shows high sensitivity and specificity in predicting DVT among pregnant women, with all true positive cases confirmed by compressed ultrasonography scans. The presence of false positives, particularly in the third trimester, underscores the need for confirmatory testing to ensure accurate diagnosis. DMMB can be an effective initial screening tool for DVT in resource-limited settings.
OGUNTONA TAIWO is a Lecturer I at the Department of Medical Biochemistry
OGUNTONA has a Ph.D in from The University of Sheffield
