MUTIU WASIU BAMIDELE

Medical Microbiology and Parasitology

At the Medical Microbiology And Parasitology department office

Appointment on Visitation important

Topic: Management Of Public Health Events Of International Concern And Infectious Diseases Outbreak

Description: My reserach focus is on infection prevention and control as well as building capacity in mitigation of infectious diseases outbreak while biobanking the pathogens for genomic surveullance for the development of therapeutics and diagnostic platform.

#	Certificate	School	Year
1.	FMCPATH MEDICAL MICROBIOLOGY (MEDICAL MICROBIOLOGY & PARASITOLOGY)	National Postgraduate Medical College of NIgeria Fellowship FMCPATh	2007

COMPARATIVE STUDY OF THE EFFICACY OF TETRACYTE TOPICAL OINTMENT (TETRACYCLINE-HCL 30MG) AND DERMAZIN (SILVER SULFAZIAZINE 25GM) IN PREVENTION AND TREATMENT OF BURN WOUND INFECTION WITH TOTAL SURFACE AREA 40% IN THE BURNS UNIT AT LAGOS STATE UNIVERSITY TEACHING HOSPITAL, IKEJA LAGOS STATE

Introduction:

Burn wound infection (BWI) remains a leading cause of morbidity and mortality in burn patients, despite advances in surgical care. Devitalized tissue provides a medium for bacterial colonization, resulting in delayed healing and poor scarring. Topical antimicrobials are central to infection prevention, particularly in the context of rising antimicrobial resistance. Silver sulfadiazine (Dermazin®) has long been the standard of care, while Tetracyte® (Tetracycline-HCL 30mg) is a newer topical agent with broad-spectrum antibacterial activity. This study evaluates their comparative efficacy in patients with burns covering less than 25% of total body surface area.

Objectives:

The trial aims to (1) compare the efficacy and tolerability of Tetracyte® and Dermazin® in preventing and treating BWI, and (2) establish the bacterial dynamics and antimicrobial susceptibility patterns of pathogens isolated from burn wounds.

Methodology:

A double-blinded, prospective, randomized controlled study will be conducted at LASUTH and Gbagada General Hospital, Lagos. Sixty adult patients with burn wounds ≤20% TBSA will be recruited and randomized into two treatment arms: Tetracyte® ointment and Dermazin® cream. Wound swabs will be collected on Day 0 and Day 7, irrigated with sterile saline, and analyzed microbiologically. Primary endpoints include clinical signs of infection and bacterial culture results on Day 7. Adverse events will be monitored, and data analyzed using IBM SPSS version 29.0.

Expected Results and Contribution:

Both agents are anticipated to reduce bacterial colonization and infection, with Tetracyte® potentially demonstrating comparable or superior activity against common burn pathogens. Findings will provide evidence for alternative topical antimicrobial strategies, inform clinical practice in resource-limited settings, and contribute to addressing antimicrobial resistance in burn wound management.

MUTIU BAMIDELE is a Senior Lecturer at the Department of Medical Microbiology and Parasitology

MUTIU has a FMCPATH MEDICAL MICROBIOLOGY in MEDICAL MICROBIOLOGY & PARASITOLOGY from National Postgraduate Medical College of NIgeria Fellowship FMCPATh