LAWAL Aminat Olajumoke

Microbiology

At the Microbiology department office

Appointment on Visitation important

Topic: STUDIES ON MULTIPLE DRUG RESISTANT ON P. AERUGINOSA ISOLATED FROM DIFFERENT SOURCES IN LAGOS STATE, NIGERIA

Description:

Introduction: Pseudomonas aeruginosa is one of the causes of hospital-acquired infections in the critically ill. It is an opportunistic pathogen that is the main cause of chronic lung infections in cystic fibrosis patients. Vulnerable people, like the immunocompromised individual, are particularly susceptible to infections.

Aims: The aim of this study was to determine the prevalence, antibiotic resistance, and genetic profiles of P. aeruginosa from a variety of sources (wound swap, inanimate surfaces, ventilators, water, urine, and blood sample in hospitals, water bodies from environment, and abbatoir water, animal waste and animal urine). And also to establish clonal relatedness and/or diversity utilizing advanced molecular techniques.

Methods: In total, 3100 clinical samples, 900 environmental samples, and 500 animal sources will be used to detect the frequency of P. aeruginosa pathogens using cultural methods and identified by standard methods. Further identification will be carried out using AP1 20E. Antimicrobial susceptibility testing, ESBL and AmpC, and resistance determinants will be done using the standard recognized procedure. Virulence and resistance genes determinant will be done using specific gene markers.

Possible Results: Positive culture will be reported of the samples using conventional culture, PCR, and Molecular methods. Multidrug-resistant P. aeruginosa will be found from different sources. The phylogenetic tree will be created and the clonal relatedness of P. aeruginosa from different sources will be determined. The results from this study will also provide information data on strains of P. aeruginosa circulating in Nigeria and will contribute to the global gene data bank thereby paving the way for a better understanding of resistance mechanisms and for instituting new intervention strategies in the areas of sanitation and waste management as well as novel antibiotics, diagnostic assay, and vaccine development.

#	Certificate	School	Year
1.	M.Sc (Medical Microbiology and Parasitology.)	University of Ilorin, Ilorin Kwara State.	2021

LAWAL Aminat is a Assistant Lecturer at the Department of Microbiology

LAWAL has a M.Sc in Medical Microbiology and Parasitology. from University of Ilorin, Ilorin Kwara State.