KUYINU ABIOLA YETUNDE

Community Health and Primary Care

At the Community Health And Primary Care department office

Appointment on Visitation important

Topic: Infection Prevention &Control- Perceptions And Practices Of Health Care Workers In Secondary Health Facilities In Lagos State

Description: Healthcare associated infections are a serious public health threat globally with potential to limit the quality and safety of health care provided to the sick. strict implementation of WHO recommended infection Prevention and Control measures at all times and particularly during outbreaks of infectious disease have potential to increase access to safe and quality health care.The aim of this study is to assess the perceptions and practices of health care workers in secondary health facilities in Lagos State with regards to provision and implementation of IPC materials and measures during the COVID-19 pandemic.

#	Certificate	School	Year
1.	MD Doctor of Medicine (Public Health & Community Medicine)	National Postgraduate Medical College of Nigeria	2021

Diagnostic Accuracy of Computer Aided Reading of Chest X-Ray in screening for pulmonary Tuberculosis in Comparison with GeneXpert

Tuberculosis (TB) remains a significant global public health challenge, ranking among the top infectious disease killers worldwide. It is caused by Mycobacterium tuberculosis which primarily affects the lungs and spreads through airborne droplets, disproportionately impacting low- and middle-income countries with high population density, poverty, and co-morbidities such as HIV. 

Nigeria is one of the 30 high-burden countries, contributing substantially to the African region’s TB caseload, with challenges in case detection exacerbated by limited access to advanced diagnostics, overcrowding in urban centres like Lagos, and overlapping symptoms with other respiratory illnesses. Early and accurate diagnosis is critical not only for individual patient outcomes but also for interrupting transmission chains and achieving the World Health Organization’s (WHO) End TB Strategy targets. In resource-constrained settings, reliance on conventional methods such as sputum smear microscopy has proven inadequate due to its low sensitivity, particularly in smear-negative or paucibacillary cases common among HIV-co-infected patients and children. 

Chest radiography (CXR) has long served as a cornerstone for screening suspected TB cases because of its widespread availability, low cost, and ability to provide rapid visual evidence of pulmonary abnormalities such as infiltrates, cavitation, or miliary patterns. However, its diagnostic performance is limited by moderate sensitivity (especially in early or extra-pulmonary disease) and poor specificity, often leading to over-diagnosis or unnecessary treatment in settings with high background prevalence of other lung pathologies.  In contrast, the GeneXpert MTB/RIF assay (Cepheid, USA) represents a major advancement as an automated, cartridge-based nucleic acid amplification test endorsed by the WHO since 2010. 

Thus by determining the diagnostic accuracy metrics of computer-aided CXR reading against GeneXpert as the reference standard, this research will provide actionable insights into its utility as a screening modality. Ultimately, it will contribute to more effective TB control strategies, better patient outcomes, and progress toward national and global TB elimination targets in a high-burden setting.

KUYINU YETUNDE is a Professor at the Department of Community Health and Primary Care

KUYINU has a MD Doctor of Medicine in Public Health & Community Medicine from National Postgraduate Medical College of Nigeria