JOHN THERESA ADEBOLA

Pharmacology

At the Pharmacology department office

Appointment on Visitation important

Topic: JA PA SYNDROME AND YOUNG HEALTH PROFESSIONALS WHO FORM THE EMERGING WORKFORCE

Description: I have in 2023 presented four seminars and two research papers on the relationship between multiple intelligences and indicators of migration and entrepreneurship in young health professionals. I have further submitted a scientific paper from ongoing studies with recommendations on how to curb the decades old japa syndrome that has been making medical education in Nigeria inefficient. I continue to investigate how educational interventions can actualize multiple intelligences in young health professionals, particularly: entrepreneurial intelligence for personal contributions, emotional intelligence to respond to local needs, scientific intelligence to be innovative, cultural intelligence for adaptability, and recognition of green pastures at home for job satisfaction. Brain drain is perhaps the crucial problem to solve for strategic nation building in Nigeria and especially for the struggling health sector, thus this line of investigations is important for me, having a Masters degree in Health Professions Education.

#	Certificate	School	Year
1.	M.Ed. (Health Professions Education)	Department of Medical Education, College of Medicine of The University of Illinois at Chicago, Chicago, Illinois, USA	2003

INVESTIGATION OF THE NON-VOLATILE CHEMICAL CONSTITUENTS OF ENTANDROPHRAGMA UTILE BARK EXTRACTS FOR ANTIBACTERIAL ACTIVITY USING CULTURES OF PROTEUS MIRABILIS, KLEBSIELLA OXYTOCA, STAPHYLOCOCCUS AUREUS, AND ESCHERICHIA COLI

Introduction: Entandrophragma utile is a timber tree. The bark is a wasted by-product of the timber industry that could be used for nutraceutical industry if its pharmacologic importance is known. We previously identified volatile constituents of the bark, some with documented biologic activity such as antibacterial activity. Objective: In this investigation we investigated the non-volatile constituents of the bark for antibacterial activity. Methods: The fresh bark was dried, pulverized and suspended as 2g powder in 25ml of different solvents distilled water, ethanol, and acetone and extracted by maceration over 10 days at 4C after which the mixture was filtered. The wet bark was chopped and 186.03g of the chopped bark was simmered in 3L of distilled water before filtration. The non volatile constituents of the E. utile bark was extracted by prolonged heating at 70C and evaporation of the filtrate over a water bath. The antimicrobial activity of the extracts was evaluated by agar well diffusion method, disc diffusion method and minimum inhibitory concentration MIC determination. Results: The results showed that the non-volatile constituent of E. utile bark and wet bark extracts in different solvents at different concentrations 0.0667 to 6667 microgram per ml had zero zone of inhibition on the growth of the 4 bacterial species. This work revealed non effectiveness of non volatile solid constituents of the bark of E. utile on four bacteria species tested. The volatile constituents of E. utile bark may thus be tested with focus on antibacterial property.Contribution to Knowledge: Changing the methods of extraction of medicinal plants from the traditional methods will yield different biologic effects from the traditional experience.

JOHN THERESA is a Associate Professor / Reader at the Department of Pharmacology

JOHN has a M.Ed. in Health Professions Education from Department of Medical Education, College of Medicine of The University of Illinois at Chicago, Chicago, Illinois, USA