Neurophysiology, Aging, Learning And Memory
At the Physiology department office
Appointment on Visitation important
Topic: Synaptic Function, Learning And Memory During Normal Ageing
Description: My current research involves studying the synaptic properties of hippocampal and cortical neurons as a basis for learning and memory. In addition my research attempts characterize neurobehavioural implications in health or disease and identify novel therapeutic targets or strategies to improve neuronal function, synaptic plasticity, learning and memory during normal ageing, health or disease.
|1.||Ph.D (Physiology)||Physiology, Lagos State University||2016|
Environmental Enrichment and Neurobehavioural Function in the BALB/c Mice
Environmental enrichment has shown to increase adult neurogenesis and improve cognitive function in different rodent models, however the functional and behavioural implications of environmental enrichment of the BALB/c kept in a typical standard housing in Nigeria laboratories is yet to be characterized. Housing and cage conditions may alter normal behavioural phenotypes of rodents. This study is aimed at assessing the implications of such environmental conditions in which animals are raised and how it may affect research outcomes. It is expected that the results would provide a basis for what type of enrichment is appropriate for the BALB/c animal model in Nigerian research laboratories and animal house facilities. In a recent pilot study with the BALB/c mice, our findings revealed that there was a significant increase in motor and cognitive function with environmental enrichment during early development in the BALB/c mice. It is hypothesized that appropriate environmental enrichment in the rodent housing or cage may preserve unique functional and behavioural phenotypes of these rodents. It is expected that environmental enrichment will help achieve reproducible research data in rodent models used for medical research in Nigeria.
IDOWU ABIMBOLA is a Senior Lecturer at the Department of Physiology
IDOWU has a Ph.D in Physiology from Physiology, Lagos State University