Meet DARAMOLA OLOLADE OORE-OLUWAPO, an Academic Staff of Lagos State University.
Reproductive Physiology
Lecturer I
Physiology
At the Physiology department office
Appointment on Visitation important
Topic: Reproductive Physiology
Description:
Alcohol consumption predisposes one to various hazards like reproductive toxicity. certain antioxidants has the credited ability to decrease oxidative stress and has been reportedly used to ameliorate reproductive damage in experimental animals. This research will investigate the mitigating abilities of a named antioxidant administration on reproductive toxicity caused by alcohol in male Wistar rats. Male Wistar rats (150-180g) will be used as the research model and dosages of drug and length of administration will be adopted from the literature. There effects will be examined on sperm profile, redox status DNA oxidative damage, anti-apoptotic factors, pro-apoptotic factors, Inflammatory markers anti-inflammatory markers and histology all in the testicular tissues.
The result will provide an extrapolated insight on the possible effects of the named antioxidant substance by those who consume alcohol.
| # | Certificate | School | Year |
|---|---|---|---|
| 1. | Ph.D (Physiology) | Department o Physiology, University of Ibadan | 2021 |
Evaluation of the effects of lycopene on alcohol-induced reproductive toxicity in Drosophila melanogaster
Alcohol is a known reproductive toxic agent. The model (Drosophila Melanogaster) has great genetic similarities with human D. melanogaster has been used in several experiments to determine the effects of alcohol on its reproductive functions and with highly informative and educative results, therefore, the effects of a named antioxidant on alcohol-induced male reproductive toxicity in Drosophila melanogaster was investigated. A survival assay was first carried out. The flies were treated for 20 days by incorporating the treatment in their meals. mating behaviours neuronal behaviours, sperm morphology and seminal vessicles were measured, also redox status were determined. other indices such as mating index were calculated from the data generated Egg count as well as offspring count were equally done. It is hoped that the experiment would provide insight on the probable capacity of a named antioxidant to mitigate the adverse effects of alcohol consumption on reproductive and neuronal indices in Drosophila melanogaster.
DARAMOLA OORE-OLUWAPO is a Lecturer I at the Department of Physiology
DARAMOLA has a Ph.D in Physiology from Department o Physiology, University of Ibadan
