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Topic: Effects Of CYP P450 And Uridine 5’-diphosphate- Glucuronosyltransferase (UGT) Enzymes On The Efficacy, Adverse Effects, And Adverse Drug-Drug Interactions Of Cannabidiol (CBD) Used As An Adjunctive Therapy In Schizophrenia
Aims of the Study
1. To determine whether adjunct use of cannabidiol (CBD) with antipsychotic drugs adequately treat and prevent relapse of schizophrenia
2. To determine the adverse effects (AEs) associated with CBD used as an adjunct treatment to antipsychotic drugs over 24 months of treatment.
3. To determine the potential adverse interactions between CBD and concomitant medications used by schizophrenic patients
|1.||D. Phil. (Cancer Science)||African Cancer Institute, Faculty of Medicine and Health Sciences, Stellenbosch University||2021|
Providing Teratology Information Services in Nigeria: The viewpoints of Physicians in Obstetrics and Gynecology speciality
Teratology Information Services centre is necessary to provide information on safety and risk of exposures during pregnancy. The survey aimed to evaluate the knowledge of medical professionals in obstetrics and gynecology in Lagos about teratogenic risk and to seek their opinions about the need for a teratology information service centre
METHODOLOGY: The study was a cross sectional survey of medical professionals. A convenience sample of doctors in the field of obstetrics and gynecology in private and public hospitals in Lagos were surveyed with a self-designed questionnaire. information was sought on nine categories covering the demography of the participants, and their views on teratogens and teratology information service centre (TISC). Completion of the survey served as consent to participate. Study was approved by HREC of Lagos Universuty Teaching Hospital.
CONCLUSION: Medical professionals in the field of obstetrics and gynecology speciality in lagos public and private hospitals felt the need for a national TISC in Nigeria and would consult regularly. if established. However, there is a need to improve the use of appropriate information resources on teratology
BADRU WASIU is a Lecturer II at the Department of Pharmacology
BADRU has a D. Phil. in Cancer Science from African Cancer Institute, Faculty of Medicine and Health Sciences, Stellenbosch University