Meet ADENOWO FATIMAH ABIOLA, an Academic Staff of Lagos State University.
Toxicogenomics, Nutraceutical Development From Natural Products,
Lecturer I
Medical Biochemistry
At the Medical Biochemistry department office
Appointment on Visitation important
Topic: Toxicogenomics And Nutraceutical Development
Description: Toxicogenomics involves the study of the effect of toxic substances on gene expression, protein express. This research interest broadly entails evaluating the safety and toxic effect of potential nutraceutical products. It involves investigating changes in gene/protein activities as well as the biological pathways/functions that respond to xenobiotic substances in animals and humans.
| # | Certificate | School | Year |
|---|---|---|---|
| 1. | Ph.D (Biochemistry) | University of Zululand, Kwadlangezwa, 3886, South Africa | 2018 |
PHYTOCHEMICAL SCREENING, INVITRO ANTIOXIDANT ASSESSMENT AND TOXICOLOGICAL EVALUATION OF EXTRACT Azanza garckeana FRUIT PULP
This study investigated the phytochemical constituents and invitro antioxidant activity of the aqueous extract of Azanza garckeana fruit pulp. Qualitative and quantitative phytochemical analyses were done using previously reported standard methods. The antioxidant activity was evaluated using 1, 1-diphenyl-2-picrylhydrazyl DPPH , ferric-reducing antioxidant power FRAP assays, nitric oxide and hydroxyl scavenging activity. The results showed that the extract contained appreciable amount of phytochemicals, with phenols and flavonoids topping the list with 38.22 mg/g and 35.88 mg/g respectively. HPLC analysis revealed the presence of important flavonoids and phenolic compounds with Nairingin and Kaempferol having the highest composition. The extract exhibited significant antioxidant activities which could be attributed to the presence of flavonoids and phenolic compounds detected in abundance in the extract. These findings revealed that the aqueous extract of Azanza garckeana fruit pulp is a rich source of phytochemicals with significant antioxidant properties; this may justify the several health claims accredited to the fruit. Hence, the fruit pulp could be exploited for the development of natural antioxidants and therapeutic agents.
ADENOWO ABIOLA is a Lecturer I at the Department of Medical Biochemistry
ADENOWO has a Ph.D in Biochemistry from University of Zululand, Kwadlangezwa, 3886, South Africa
